Long-read-based single sperm genome sequencing for chromosome-wide haplotype phasing of both SNPs and SVs

Although localized haploid phasing can be achieved using long read genome sequencing without parental data, reliable chromosome-scale phasing remains a great challenge. Given that sperm is a natural haploid cell, single-sperm genome sequencing can provide a chromosome-wide phase signal. Due to the l...

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Detalles Bibliográficos
Autores principales: Xie, Haoling, Li, Wen, Guo, Yuqing, Su, Xinjie, Chen, Kexuan, Wen, Lu, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450174/
https://www.ncbi.nlm.nih.gov/pubmed/37351613
http://dx.doi.org/10.1093/nar/gkad532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450174/
https://www.ncbi.nlm.nih.gov/pubmed/37351613
http://dx.doi.org/10.1093/nar/gkad532

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