N-terminal alanine-rich (NTAR) sequences drive precise start codon selection resulting in elevated translation of multiple proteins including ERK1/2

We report the discovery of N-terminal alanine-rich sequences, which we term NTARs, that act in concert with their native 5′-untranslated regions to promote selection of the proper start codon. NTARs also facilitate efficient translation initiation while limiting the production of non-functional poly...

Descripción completa

Detalles Bibliográficos
Autores principales: Buscà, Roser, Onesto, Cercina, Egensperger, Mylène, Pouysségur, Jacques, Pagès, Gilles, Lenormand, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450180/
https://www.ncbi.nlm.nih.gov/pubmed/37414542
http://dx.doi.org/10.1093/nar/gkad528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450180/
https://www.ncbi.nlm.nih.gov/pubmed/37414542
http://dx.doi.org/10.1093/nar/gkad528

Ejemplares similares