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N-terminal alanine-rich (NTAR) sequences drive precise start codon selection resulting in elevated translation of multiple proteins including ERK1/2
We report the discovery of N-terminal alanine-rich sequences, which we term NTARs, that act in concert with their native 5′-untranslated regions to promote selection of the proper start codon. NTARs also facilitate efficient translation initiation while limiting the production of non-functional poly...
Autores principales: | Buscà, Roser, Onesto, Cercina, Egensperger, Mylène, Pouysségur, Jacques, Pagès, Gilles, Lenormand, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450180/ https://www.ncbi.nlm.nih.gov/pubmed/37414542 http://dx.doi.org/10.1093/nar/gkad528 |
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