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Role of DNA–DNA sliding friction and nonequilibrium dynamics in viral genome ejection and packaging

Many viruses eject their DNA via a nanochannel in the viral shell, driven by internal forces arising from the high-density genome packing. The speed of DNA exit is controlled by friction forces that limit the molecular mobility, but the nature of this friction is unknown. We introduce a method to pr...

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Detalles Bibliográficos
Autores principales: Fizari, Mounir, Keller, Nicholas, Jardine, Paul J, Smith, Douglas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450192/
https://www.ncbi.nlm.nih.gov/pubmed/37449417
http://dx.doi.org/10.1093/nar/gkad582