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Updated protein domain annotation of the PARP protein family sheds new light on biological function

AlphaFold2 and related computational tools have greatly aided studies of structural biology through their ability to accurately predict protein structures. In the present work, we explored AF2 structural models of the 17 canonical members of the human PARP protein family and supplemented this analys...

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Detalles Bibliográficos
Autores principales: Suskiewicz, Marcin J, Munnur, Deeksha, Strømland, Øyvind, Yang, Ji-Chun, Easton, Laura E, Chatrin, Chatrin, Zhu, Kang, Baretić, Domagoj, Goffinont, Stéphane, Schuller, Marion, Wu, Wing-Fung, Elkins, Jonathan M, Ahel, Dragana, Sanyal, Sumana, Neuhaus, David, Ahel, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450202/
https://www.ncbi.nlm.nih.gov/pubmed/37326024
http://dx.doi.org/10.1093/nar/gkad514