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RNA polymerase redistribution supports growth in E. coli strains with a minimal number of rRNA operons

Bacterial transcription by RNA polymerase (RNAP) is spatially organized. RNAPs transcribing highly expressed genes locate in the nucleoid periphery, and form clusters in rich medium, with several studies linking RNAP clustering and transcription of rRNA (rrn). However, the nature of RNAP clusters an...

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Detalles Bibliográficos
Autores principales: Fan, Jun, El Sayyed, Hafez, Pambos, Oliver J, Stracy, Mathew, Kyropoulos, Jingwen, Kapanidis, Achillefs N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450203/
https://www.ncbi.nlm.nih.gov/pubmed/37351576
http://dx.doi.org/10.1093/nar/gkad511