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Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine

Hepatocyte nuclear factor 4-alpha (HNF4α) drives a complex array of transcriptional programs across multiple organs. Beyond its previously documented function in the liver, HNF4α has crucial roles in the kidney, intestine, and pancreas. In the intestine, a multitude of functions have been attributed...

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Detalles Bibliográficos
Autores principales: Vemuri, Kiranmayi, Radi, Sarah H., Sladek, Frances M., Verzi, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450339/
https://www.ncbi.nlm.nih.gov/pubmed/37635981
http://dx.doi.org/10.3389/fendo.2023.1232569