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Eph receptor B6 shapes a cold immune microenvironment, inhibiting anti-cancer immunity and immunotherapy response in bladder cancer

BACKGROUND: The role of Eph receptors and related ephrin (EFN) ligands (as the largest family of transmembrane-bound RTKs) in immunomodulation in many types of cancer, especially bladder cancer (BLCA), is scarcely known. METHODS: A pan-cancer dataset was retrieved from The Cancer Genome Atlas (TCGA)...

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Detalles Bibliográficos
Autores principales: Jia, Xiaolong, Zhang, Dongxu, Zhou, Cheng, Yan, Zejun, Jiang, Zhaohui, Xie, Liping, Jiang, Junhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450340/
https://www.ncbi.nlm.nih.gov/pubmed/37637034
http://dx.doi.org/10.3389/fonc.2023.1175183