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Disruption of Col9a2 expression leads to defects in osteochondral homeostasis and osteoarthritis-like phenotype in mice

BACKGROUND/OBJECTIVE: As one of the branched chains of Type IX collagen (Col9), Collagen IX alpha2 (Col9a2) has been reported to be associated with several orthopedic conditions. However, the relationship between Col9a2 and knee osteoarthritis (KOA) remains to be elucidated. METHODS: To probe the re...

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Detalles Bibliográficos
Autores principales: Dong, Rui, Xu, Huihui, Wang, Pinger, Fang, Liang, Xiao, Luwei, Lv, Shuaijie, Tong, Peijian, Jin, Hongting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450353/
https://www.ncbi.nlm.nih.gov/pubmed/37635809
http://dx.doi.org/10.1016/j.jot.2023.08.005