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Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy model
BACKGROUND: Dolutegravir (DTG) is a recommended first-line regimen for all people with Human Immunodeficiency Virus (HIV) infection. Initial findings from Botswana, a country with no folate fortification program, showed an elevated prevalence of neural tube defects (NTDs) with peri-conceptional expo...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450420/ https://www.ncbi.nlm.nih.gov/pubmed/37586112 http://dx.doi.org/10.1016/j.ebiom.2023.104762 |