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Roles for diacylglycerol in synaptic vesicle priming and release revealed by complete reconstitution of core protein machinery

Here, we introduce the full functional reconstitution of genetically validated core protein machinery (SNAREs, Munc13, Munc18, Synaptotagmin, and Complexin) for synaptic vesicle priming and release in a geometry that enables detailed characterization of the fate of docked vesicles both before and af...

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Detalles Bibliográficos
Autores principales: Kalyana Sundaram, R. Venkat, Chatterjee, Atrouli, Bera, Manindra, Grushin, Kirill, Panda, Aniruddha, Li, Feng, Coleman, Jeff, Lee, Seong, Ramakrishnan, Sathish, Ernst, Andreas M., Gupta, Kallol, Rothman, James E., Krishnakumar, Shyam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450444/
https://www.ncbi.nlm.nih.gov/pubmed/37590407
http://dx.doi.org/10.1073/pnas.2309516120