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Roles for diacylglycerol in synaptic vesicle priming and release revealed by complete reconstitution of core protein machinery
Here, we introduce the full functional reconstitution of genetically validated core protein machinery (SNAREs, Munc13, Munc18, Synaptotagmin, and Complexin) for synaptic vesicle priming and release in a geometry that enables detailed characterization of the fate of docked vesicles both before and af...
Autores principales: | Kalyana Sundaram, R. Venkat, Chatterjee, Atrouli, Bera, Manindra, Grushin, Kirill, Panda, Aniruddha, Li, Feng, Coleman, Jeff, Lee, Seong, Ramakrishnan, Sathish, Ernst, Andreas M., Gupta, Kallol, Rothman, James E., Krishnakumar, Shyam S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450444/ https://www.ncbi.nlm.nih.gov/pubmed/37590407 http://dx.doi.org/10.1073/pnas.2309516120 |
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