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Reversal of an existing hearing loss by gene activation in Spns2 mutant mice
Hearing loss is highly heterogeneous, but one common form involves a failure to maintain the local ionic environment of the sensory hair cells reflected in a reduced endocochlear potential. We used a genetic approach to ask whether this type of pathology can be reversed, using the Spns2(tm1a) mouse...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450448/ https://www.ncbi.nlm.nih.gov/pubmed/37552762 http://dx.doi.org/10.1073/pnas.2307355120 |