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α-Synuclein Aggregation Is Triggered by Oligomeric Amyloid-β 42 via Heterogeneous Primary Nucleation

[Image: see text] An increasing number of cases where amyloids of different proteins are found in the same patient are being reported. This observation complicates diagnosis and clinical intervention. Amyloids of the amyloid-β peptide or the protein α-synuclein are traditionally considered hallmarks...

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Detalles Bibliográficos
Autores principales: Vadukul, Devkee M., Papp, Marcell, Thrush, Rebecca J., Wang, Jielei, Jin, Yiyun, Arosio, Paolo, Aprile, Francesco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450681/
https://www.ncbi.nlm.nih.gov/pubmed/37556728
http://dx.doi.org/10.1021/jacs.3c03212