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A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers

[Image: see text] The amyloid-β (Aβ) peptide is associated with the development of Alzheimer’s disease and is known to form highly neurotoxic prefibrillar oligomeric aggregates, which are difficult to study due to their transient, low-abundance, and heterogeneous nature. To obtain high-resolution in...

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Detalles Bibliográficos
Autores principales: Khaled, Mohammed, Rönnbäck, Isabel, Ilag, Leopold L., Gräslund, Astrid, Strodel, Birgit, Österlund, Nicklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450692/
https://www.ncbi.nlm.nih.gov/pubmed/37555670
http://dx.doi.org/10.1021/jacs.3c03980