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T Cell Clonal Analysis Using Single-cell RNA Sequencing and Reference Maps

T cells are endowed with T-cell antigen receptors (TCR) that give them the capacity to recognize specific antigens and mount antigen-specific adaptive immune responses. Because TCR sequences are distinct in each naïve T cell, they serve as molecular barcodes to track T cells with clonal relatedness...

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Detalles Bibliográficos
Autores principales: Andreatta, Massimo, Gueguen, Paul, Borcherding, Nicholas, Carmona, Santiago J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450729/
https://www.ncbi.nlm.nih.gov/pubmed/37638293
http://dx.doi.org/10.21769/BioProtoc.4735