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The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules
During mitosis, microtubules in the spindle turn over continuously. At spindle poles, where microtubule minus ends are concentrated, microtubule nucleation and depolymerization, the latter required for poleward microtubule flux, happen side by side. How these seemingly antagonistic processes of nucl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450741/ https://www.ncbi.nlm.nih.gov/pubmed/37615667 http://dx.doi.org/10.1083/jcb.202304020 |