Oral fibroblasts rescue osteogenic differentiation of mesenchymal stem cells after exposure to Zoledronic acid in a paracrine effect

Background: Medication-related osteonecrosis of the jaw is a serious complication that develops in oncologic patients treated with Zoledronic acid. Although used for over 30 years, the influence of Zoledronic acid on bone has been thoroughly investigated, mainly on osteoclasts. While decreasing oste...

Descripción completa

Detalles Bibliográficos
Autores principales: Berg, Tal, Doppelt-Flikshtain, Ofri, Coyac, Benjamin R., Zigdon-Giladi, Hadar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450747/
https://www.ncbi.nlm.nih.gov/pubmed/37637413
http://dx.doi.org/10.3389/fphar.2023.1172705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450747/
https://www.ncbi.nlm.nih.gov/pubmed/37637413
http://dx.doi.org/10.3389/fphar.2023.1172705

Ejemplares similares