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Development and Applications of Chimera Platforms for Tyrosine Phosphorylation
[Image: see text] Chimeric small molecules that induce post-translational modification (PTM) on a target protein by bringing it into proximity to a PTM-inducing enzyme are furnishing novel modalities to perturb protein function. Despite recent advances, such molecules are unavailable for a critical...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450875/ https://www.ncbi.nlm.nih.gov/pubmed/37637727 http://dx.doi.org/10.1021/acscentsci.3c00200 |