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Development and Applications of Chimera Platforms for Tyrosine Phosphorylation

[Image: see text] Chimeric small molecules that induce post-translational modification (PTM) on a target protein by bringing it into proximity to a PTM-inducing enzyme are furnishing novel modalities to perturb protein function. Despite recent advances, such molecules are unavailable for a critical...

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Detalles Bibliográficos
Autores principales: Pergu, Rajaiah, Shoba, Veronika M., Chaudhary, Santosh K., Munkanatta Godage, Dhanushka N. P., Deb, Arghya, Singha, Santanu, Dhawa, Uttam, Singh, Prashant, Anokhina, Viktoriya, Singh, Sameek, Siriwardena, Sachini U., Choudhary, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450875/
https://www.ncbi.nlm.nih.gov/pubmed/37637727
http://dx.doi.org/10.1021/acscentsci.3c00200