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450 million years in the making: mapping the evolutionary foundations of germinal centers

Germinal centers (GCs) are distinct microanatomical structures that form in the secondary lymphoid organs of endothermic vertebrates (i.e., mammals and some birds). Within GCs, B cells undergo a Darwinian selection process to identify clones which can respond to pathogen insult as well as affinity m...

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Detalles Bibliográficos
Autores principales: Matz, Hanover, Dooley, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450919/
https://www.ncbi.nlm.nih.gov/pubmed/37638014
http://dx.doi.org/10.3389/fimmu.2023.1245704