Characterization, complete genome sequencing, and CRISPR/Cas9 system-based decontamination of a novel Escherichia coli phage TR1 from fermentation substrates

Phage contamination has become a major concern for industrial bacteria, such as Escherichia coli BL21(DE3), used in fermentation processes. Herein, we report a CRISPR/Cas9 defense system-based strategy to precisely prey and degrade phage DNA to decontaminate target phages. First, we isolated a novel...

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Detalles Bibliográficos
Autores principales: Dong, Yuqi, Huang, Yunfei, Fan, Huahao, Song, Lihua, An, Xiaoping, Xu, Shan, Li, Mengzhe, Tong, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450929/
https://www.ncbi.nlm.nih.gov/pubmed/37637117
http://dx.doi.org/10.3389/fmicb.2023.1230775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450929/
https://www.ncbi.nlm.nih.gov/pubmed/37637117
http://dx.doi.org/10.3389/fmicb.2023.1230775

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