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Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors

Introduction: The cannabinoid receptor (CBR) subtypes 1 (CB(1)R) and 2 (CB(2)R) are key components of the endocannabinoid system (ECS), playing a central role in the control of peripheral pain, inflammation and the immune response, with further roles in the endocrine regulation of food intake and en...

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Detalles Bibliográficos
Autores principales: Scott-Dennis, Morgan, Rafani, Fikri A., Yi, Yicheng, Perera, Themiya, Harwood, Clare R., Guba, Wolfgang, Rufer, Arne C., Grether, Uwe, Veprintsev, Dmitry B., Sykes, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450933/
https://www.ncbi.nlm.nih.gov/pubmed/37637423
http://dx.doi.org/10.3389/fphar.2023.1158091