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Dexpanthenol improved stem cells against cisplatin-induced kidney injury by inhibition of TNF-α, TGFβ-1, β-catenin, and fibronectin pathways

INTRODUCTION: Cisplatin interacts with DNA and induces an immunological response and reactive oxygen species, which are nephrotoxic mediators. Stem cells self-renew through symmetric divisions and can develop into other cell types due to their multipotency. Dexpanthenol has been proven to protect ag...

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Detalles Bibliográficos
Autores principales: El-Dawy, Khalifa, Barakat, Nashwa, Ali, Hala, Sindi, Ikhlas A., Adly, Heba M., Saleh, Saleh A.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450985/
https://www.ncbi.nlm.nih.gov/pubmed/37635837
http://dx.doi.org/10.1016/j.sjbs.2023.103773