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Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly

[Image: see text] Catalytic RNAs or ribozymes are considered to be central to primordial biology. Most ribozymes require moderate to high concentrations of divalent cations such as Mg(2+) to fold into their catalytically competent structures and perform catalysis. However, undesirable effects of Mg(...

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Detalles Bibliográficos
Autores principales: DasGupta, Saurja, Zhang, Stephanie, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451029/
https://www.ncbi.nlm.nih.gov/pubmed/37637737
http://dx.doi.org/10.1021/acscentsci.3c00547