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Exploring Antibiotic-Potentiating Effects of Tobramycin–Deferiprone Conjugates in Pseudomonas aeruginosa

Metal ions, including Fe(3+), affect the target site binding of some antibiotics and control the porin- and siderophore-mediated uptake of antibiotics. Amphiphilic tobramycins are an emerging class of antibiotic potentiators capable of synergizing with multiple classes of antibiotics against Gram-ne...

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Detalles Bibliográficos
Autores principales: Gandhi, Karan, Dhiman, Shiv, Arora, Rajat, Ramirez, Danzel Marie, Ramirez, Danyel, Arthur, Gilbert, Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451322/
https://www.ncbi.nlm.nih.gov/pubmed/37627681
http://dx.doi.org/10.3390/antibiotics12081261