SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS

Cancer cells show increased glutamine consumption. The glutaminase (GLS) enzyme controls a limiting step in glutamine catabolism. Breast tumors, especially the triple-negative subtype, have a high expression of GLS. Our recent study demonstrated that GLS activity and ammonia production are inhibited...

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Detalles Bibliográficos
Autores principales: Barreca, Federica, Aventaggiato, Michele, Vitiello, Laura, Sansone, Luigi, Russo, Matteo Antonio, Mai, Antonello, Valente, Sergio, Tafani, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451763/
https://www.ncbi.nlm.nih.gov/pubmed/37627630
http://dx.doi.org/10.3390/antiox12081635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451763/
https://www.ncbi.nlm.nih.gov/pubmed/37627630
http://dx.doi.org/10.3390/antiox12081635

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