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The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy

Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections. This bacterium exhibits both intrinsic resistance to various antipseudomonal agents and acquired resistance against nearly all a...

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Detalles Bibliográficos
Autores principales: Avakh, Asiyeh, Grant, Gary D., Cheesman, Matthew J., Kalkundri, Tejaswini, Hall, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451789/
https://www.ncbi.nlm.nih.gov/pubmed/37627724
http://dx.doi.org/10.3390/antibiotics12081304