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The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections. This bacterium exhibits both intrinsic resistance to various antipseudomonal agents and acquired resistance against nearly all a...
Autores principales: | Avakh, Asiyeh, Grant, Gary D., Cheesman, Matthew J., Kalkundri, Tejaswini, Hall, Susan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451789/ https://www.ncbi.nlm.nih.gov/pubmed/37627724 http://dx.doi.org/10.3390/antibiotics12081304 |
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