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Clinical Experience with Off-Label Intrathecal Administration of Selected Antibiotics in Adults: An Overview with Pharmacometric Considerations

Drain-associated intracerebral infections are life-threatening emergencies. Their treatment is challenging due to the limited penetration of antibiotics to the site of infection, resulting in potentially inadequate exposure. The emergence of multidrug-resistant pathogens might force the use of off-l...

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Detalles Bibliográficos
Autores principales: Muller, Anouk E., van Vliet, Peter, Koch, Birgit C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451962/
https://www.ncbi.nlm.nih.gov/pubmed/37627711
http://dx.doi.org/10.3390/antibiotics12081291