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The Importance of the “Time Factor” for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors
SIMPLE SUMMARY: Protein lysine acetylation is, with phosphorylation, the most common regulatory post-translational modification of proteins. Histone deacetylases (HDAC) catalyze the removal of acetyl groups from histone and non-histone proteins, participating in the modulation of several pathways. H...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452033/ https://www.ncbi.nlm.nih.gov/pubmed/37626935 http://dx.doi.org/10.3390/biology12081049 |