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The Importance of the “Time Factor” for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors

SIMPLE SUMMARY: Protein lysine acetylation is, with phosphorylation, the most common regulatory post-translational modification of proteins. Histone deacetylases (HDAC) catalyze the removal of acetyl groups from histone and non-histone proteins, participating in the modulation of several pathways. H...

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Detalles Bibliográficos
Autores principales: Cellupica, Edoardo, Caprini, Gianluca, Fossati, Gianluca, Mirdita, Doris, Cordella, Paola, Marchini, Mattia, Rocchio, Ilaria, Sandrone, Giovanni, Stevenazzi, Andrea, Vergani, Barbara, Steinkühler, Christian, Vanoni, Maria Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452033/
https://www.ncbi.nlm.nih.gov/pubmed/37626935
http://dx.doi.org/10.3390/biology12081049