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Copper(II) Complexes with Carnosine Conjugates of Hyaluronic Acids at Different Dipeptide Loading Percentages Behave as Multiple SOD Mimics and Stimulate Nrf2 Translocation and Antioxidant Response in In Vitro Inflammatory Model

A series of copper(II) complexes with the formula [Cu(2+)Hy(x)Car%] varying the molecular weight (MW) of Hyaluronic acid (Hy, x = 200 or 700 kDa) conjugated with carnosine (Car) present at different loading were synthesized and characterized via different spectroscopic techniques. The metal complexe...

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Detalles Bibliográficos
Autores principales: Bellia, Francesco, Lanza, Valeria, Naletova, Irina, Tomasello, Barbara, Ciaffaglione, Valeria, Greco, Valentina, Sciuto, Sebastiano, Amico, Pietro, Inturri, Rosanna, Vaccaro, Susanna, Campagna, Tiziana, Attanasio, Francesco, Tabbì, Giovanni, Rizzarelli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452038/
https://www.ncbi.nlm.nih.gov/pubmed/37627627
http://dx.doi.org/10.3390/antiox12081632