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Modulating Hyperpolarization-Activated Cation Currents through Small Molecule Perturbations: Magnitude and Gating Control

The hyperpolarization-activated cation current (I(h)) exhibits a slowly activating time course of the current (I(h)) when the cell membrane is hyperpolarized for an extended duration. It is involved in generating electrical activity in various excitable cells. Numerous structurally distinct compound...

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Detalles Bibliográficos
Autores principales: Chen, Cheng-Shih, So, Edmund Cheung, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452073/
https://www.ncbi.nlm.nih.gov/pubmed/37626674
http://dx.doi.org/10.3390/biomedicines11082177