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The Impact of Muscarinic Antagonism on Psychosis-Relevant Behaviors and Striatal [(11)C] Raclopride Binding in Tau Mouse Models of Alzheimer’s Disease

Psychosis that occurs over the course of Alzheimer’s disease (AD) is associated with increased caregiver burden and a more rapid cognitive and functional decline. To find new treatment targets, studies modeling psychotic conditions traditionally employ agents known to induce psychosis, utilizing out...

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Detalles Bibliográficos
Autores principales: Jimenez, Heidy, Carrion, Joseph, Adrien, Leslie, Wolin, Adam, Eun, John, Cinamon, Ezra, Chang, Eric H., Davies, Peter, Vo, An, Koppel, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452133/
https://www.ncbi.nlm.nih.gov/pubmed/37626588
http://dx.doi.org/10.3390/biomedicines11082091