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Preparation of Fibrinogen-Depleted Human Platelet Lysate to Support Heparin-Free Expansion of Umbilical Cord-Derived Mesenchymal Stem Cells

SIMPLE SUMMARY: The use of fetal bovine serum (FBS) in the manufacturing and production of therapeutic products is discouraged by the regulatory authorities due to the risk of zoonoses and xenogeneic immune reactions. Human platelet lysate (hPL) is suggested as an alternative to FBS for in vitro cel...

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Detalles Bibliográficos
Autores principales: Kee, Li Ting, Lee, Yi Ting, Ng, Chiew Yong, Hassan, Muhammad Najib Fathi, Ng, Min Hwei, Mahmood, Zalina, Abdul Aziz, Suria, Law, Jia Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452143/
https://www.ncbi.nlm.nih.gov/pubmed/37626970
http://dx.doi.org/10.3390/biology12081085