REGA-SIGN: Development of a Novel Set of NanoBRET-Based G Protein Biosensors

Despite G protein-coupled receptors (GPCRs) being important theapeutic targets, the signaling properties of many GPCRs remain poorly characterized. GPCR activation primarily initiates heterotrimeric G protein signaling. To detect ligand-induced G protein activation, Bioluminescence Resonance Energy...

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Detalles Bibliográficos
Autores principales: Boon, Katrijn, Vanalken, Nathan, Meyen, Eef, Schols, Dominique, Van Loy, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452170/
https://www.ncbi.nlm.nih.gov/pubmed/37622853
http://dx.doi.org/10.3390/bios13080767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452170/
https://www.ncbi.nlm.nih.gov/pubmed/37622853
http://dx.doi.org/10.3390/bios13080767

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