Synthesis and Biological Evaluation of Cyclobutane-Based β3 Integrin Antagonists: A Novel Approach to Targeting Integrins for Cancer Therapy

SIMPLE SUMMARY: The integrin family of cell surface proteins plays an important role in the development and spread of cancers. Therefore, drugs which inhibit integrins should make effective cancer treatments. Most potential drugs developed so far target a single integrin and have not proved effectiv...

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Detalles Bibliográficos
Autores principales: Sutherland, Mark, Gordon, Andrew, Al-Shammari, Fatemah O. F. O., Throup, Adam, Cilia La Corte, Amy, Philippou, Helen, Shnyder, Steven D., Patterson, Laurence H., Sheldrake, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452181/
https://www.ncbi.nlm.nih.gov/pubmed/37627051
http://dx.doi.org/10.3390/cancers15164023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452181/
https://www.ncbi.nlm.nih.gov/pubmed/37627051
http://dx.doi.org/10.3390/cancers15164023

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