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Metabolic Reprogramming toward Aerobic Glycolysis and the Gut Microbiota Involved in the Brain Amyloid Pathology
SIMPLE SUMMARY: Amyloid-β toxicity is attributed to oligomer and fibrillar amyloid-β, which either damages the neurons or initiates an intracellular signaling cascade toward neuronal cell death. In addition to the amyloid-β aggregation, an emerging hallmark of Alzheimer’s disease is the metabolic re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452252/ https://www.ncbi.nlm.nih.gov/pubmed/37626967 http://dx.doi.org/10.3390/biology12081081 |