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Metabolic Reprogramming toward Aerobic Glycolysis and the Gut Microbiota Involved in the Brain Amyloid Pathology

SIMPLE SUMMARY: Amyloid-β toxicity is attributed to oligomer and fibrillar amyloid-β, which either damages the neurons or initiates an intracellular signaling cascade toward neuronal cell death. In addition to the amyloid-β aggregation, an emerging hallmark of Alzheimer’s disease is the metabolic re...

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Detalles Bibliográficos
Autores principales: Murai, Toshiyuki, Matsuda, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452252/
https://www.ncbi.nlm.nih.gov/pubmed/37626967
http://dx.doi.org/10.3390/biology12081081