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Role of Syndecan-4 in the Inhibition of Articular Cartilage Degeneration in Osteoarthritis

Despite its widespread existence, there are relatively few drugs that can inhibit the progression of osteoarthritis (OA). Syndecan-4 (SDC4) is a transmembrane heparan sulfate proteoglycan that modulates cellular interactions with the extracellular matrix. Upregulated SDC4 expression in articular car...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshio, Hasegawa, Masahiro, Iino, Takahiro, Imanaka-Yoshida, Kyoko, Sudo, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452293/
https://www.ncbi.nlm.nih.gov/pubmed/37626753
http://dx.doi.org/10.3390/biomedicines11082257