Deletion of Gtf2i via Systemic Administration of AAV-PHP.eB Virus Increases Social Behavior in a Mouse Model of a Neurodevelopmental Disorder

Williams syndrome (WS) is a neurodevelopmental disorder characterized by distinctive cognitive and personality profiles which also impacts various physiological systems. The syndrome arises from the deletion of about 25 genes located on chromosome 7q11.23, including Gtf2i. Prior research indicated a...

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Detalles Bibliográficos
Autores principales: Ophir, Omer, Levy, Gilad, Bar, Ela, Kimchi Feldhorn, Omri, Rokach, May, Elad Sfadia, Galit, Barak, Boaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452363/
https://www.ncbi.nlm.nih.gov/pubmed/37626769
http://dx.doi.org/10.3390/biomedicines11082273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452363/
https://www.ncbi.nlm.nih.gov/pubmed/37626769
http://dx.doi.org/10.3390/biomedicines11082273

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