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Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System

The process of identifying and approving a new drug is a time-consuming and expensive procedure. One of the biggest issues to overcome is the risk of hepatotoxicity, which is one of the main reasons for drug withdrawal from the market. While animal models are the gold standard in preclinical drug te...

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Detalles Bibliográficos
Autores principales: Calamaio, Serena, Serzanti, Marialaura, Boniotti, Jennifer, Fra, Annamaria, Garrafa, Emirena, Cominelli, Manuela, Verardi, Rosanna, Poliani, Pietro Luigi, Dotti, Silvia, Villa, Riccardo, Mazzoleni, Giovanna, Dell’Era, Patrizia, Steimberg, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452373/
https://www.ncbi.nlm.nih.gov/pubmed/37626611
http://dx.doi.org/10.3390/biomedicines11082114