Effect of Mesenchymal Stem Cells Overexpressing BMP-9 Primed with Hypoxia on BMP Targets, Osteoblast Differentiation and Bone Repair

SIMPLE SUMMARY: Bone formation is regulated by proteins such as bone morphogenetic proteins (BMPs) as well as by oxygen. We previously demonstrated that cell therapy using stem cells genetically modified to express BMP-9 enhances bone formation in skull defects. Here, it was evaluated the effect of...

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Detalles Bibliográficos
Autores principales: Paz, Jessica Emanuella Rocha Moura, Adolpho, Leticia Faustino, Ramos, Jaqueline Isadora Reis, Bighetti-Trevisan, Rayana Longo, Calixto, Robson Diego, Oliveira, Fabiola Singaretti, Almeida, Adriana Luisa Gonçalves, Beloti, Marcio Mateus, Rosa, Adalberto Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452403/
https://www.ncbi.nlm.nih.gov/pubmed/37627031
http://dx.doi.org/10.3390/biology12081147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452403/
https://www.ncbi.nlm.nih.gov/pubmed/37627031
http://dx.doi.org/10.3390/biology12081147

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