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Long-Term Culturing of FreeStyle 293-F Cells Affects Immunoglobulin G Glycome Composition

Glycosylation of IgG regulates the effector function of this antibody in the immune response. Glycosylated IgG is a potent therapeutic used for both research and clinical purposes. While there is ample research on how different cell culture conditions affect IgG glycosylation, the data are missing o...

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Detalles Bibliográficos
Autores principales: Lukšić, Fran, Mijakovac, Anika, Josipović, Goran, Vičić Bočkor, Vedrana, Krištić, Jasminka, Cindrić, Ana, Vinicki, Martina, Rokić, Filip, Vugrek, Oliver, Lauc, Gordan, Zoldoš, Vlatka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452533/
https://www.ncbi.nlm.nih.gov/pubmed/37627310
http://dx.doi.org/10.3390/biom13081245