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Wiggle and Shake: Managing and Exploiting Conformational Dynamics during Proteasome Biogenesis
The 26S proteasome is the largest and most complicated protease known, and changes to proteasome assembly or function contribute to numerous human diseases. Assembly of the 26S proteasome from its ~66 individual polypeptide subunits is a highly orchestrated process requiring the concerted actions of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452565/ https://www.ncbi.nlm.nih.gov/pubmed/37627288 http://dx.doi.org/10.3390/biom13081223 |