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Icariin activates far upstream element binding protein 1 to regulate hypoxia-inducible factor-1α and hypoxia-inducible factor-2α signaling and benefits chondrocytes

Icariin (ICA) is a typical flavonoid glycoside derived from epimedium plants. It has both anabolic and anti-catabolic effects to improve bone mineral density and reduce bone microstructural degradation. However, the effect and underlying mechanism of ICA on the proliferation and metabolism of chondr...

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Detalles Bibliográficos
Autores principales: Wang, Pengzhen, Zhu, Pingping, Zhang, Shaoheng, Yuan, Wei, Liu, Zhihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452614/
https://www.ncbi.nlm.nih.gov/pubmed/37637163
http://dx.doi.org/10.7717/peerj.15917