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Icariin activates far upstream element binding protein 1 to regulate hypoxia-inducible factor-1α and hypoxia-inducible factor-2α signaling and benefits chondrocytes
Icariin (ICA) is a typical flavonoid glycoside derived from epimedium plants. It has both anabolic and anti-catabolic effects to improve bone mineral density and reduce bone microstructural degradation. However, the effect and underlying mechanism of ICA on the proliferation and metabolism of chondr...
Autores principales: | Wang, Pengzhen, Zhu, Pingping, Zhang, Shaoheng, Yuan, Wei, Liu, Zhihe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452614/ https://www.ncbi.nlm.nih.gov/pubmed/37637163 http://dx.doi.org/10.7717/peerj.15917 |
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