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Notch, SUMOylation, and ESR-Mediated Signalling Are the Main Molecular Pathways Showing Significantly Different Epimutation Scores between Expressing or Not Oestrogen Receptor Breast Cancer in Three Public EWAS Datasets

SIMPLE SUMMARY: The study compares two groups of breast cancer (BC) identified by estrogen receptor (ER) expression, using an epimutation score calculated from three public methylation datasets, based on the presence of epimutations and on the deviation amplitude of the methylation outlier value. Fi...

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Detalles Bibliográficos
Autores principales: Corsaro, Luigi, Gambino, Vincenzo Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452656/
https://www.ncbi.nlm.nih.gov/pubmed/37627137
http://dx.doi.org/10.3390/cancers15164109