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Local Control Model of a Human Ventricular Myocyte: An Exploration of Frequency-Dependent Changes and Calcium Sparks

Calcium (Ca(2+)) sparks are the elementary events of excitation–contraction coupling, yet they are not explicitly represented in human ventricular myocyte models. A stochastic ventricular cardiomyocyte human model that adapts to intracellular Ca(2+) ([Ca(2+)](i)) dynamics, spark regulation, and freq...

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Detalles Bibliográficos
Autores principales: Alvarez, Jerome Anthony E., Jafri, M. Saleet, Ullah, Aman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452762/
https://www.ncbi.nlm.nih.gov/pubmed/37627324
http://dx.doi.org/10.3390/biom13081259