Deleterious Interaction between the Neurosteroid (3α,5α)3-Hydroxypregnan-20-One (3α,5α-THP) and the Mu-Opioid System Activation during Forced Swim Stress in Rats

The neurosteroid 3α,5α-THP is a potent GABA(A) receptor-positive modulator and its regulatory action on the HPA axis stress response has been reported in numerous preclinical and clinical studies. We previously demonstrated that 3α,5α-THP down-regulation of HPA axis activity during stress is sex-, b...

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Detalles Bibliográficos
Autores principales: Boero, Giorgia, McFarland, Minna H., Tyler, Ryan E., O’Buckley, Todd K., Chéry, Samantha L., Robinson, Donita L., Besheer, Joyce, Morrow, A. Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452864/
https://www.ncbi.nlm.nih.gov/pubmed/37627270
http://dx.doi.org/10.3390/biom13081205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452864/
https://www.ncbi.nlm.nih.gov/pubmed/37627270
http://dx.doi.org/10.3390/biom13081205

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