Trem2 Enhances Demyelination in the Csf1r(+/−) Mouse Model of Leukoencephalopathy

Colony-stimulating factor-1 receptor (CSF-1R)-related leukoencephalopathy (CRL) is a neurodegenerative disease that triggers early demyelination, leading to an adult-onset dementia. Triggering receptor expressed on myeloid cells-2 (TREM2) is a microglial receptor that promotes the activation of micr...

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Detalles Bibliográficos
Autores principales: Biundo, Fabrizio, Chitu, Violeta, Gökhan, Şölen, Chen, Edward, Oppong-Asare, Jude, Stanley, E. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452898/
https://www.ncbi.nlm.nih.gov/pubmed/37626591
http://dx.doi.org/10.3390/biomedicines11082094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452898/
https://www.ncbi.nlm.nih.gov/pubmed/37626591
http://dx.doi.org/10.3390/biomedicines11082094

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