Cargando…

Trem2 Enhances Demyelination in the Csf1r(+/−) Mouse Model of Leukoencephalopathy

Colony-stimulating factor-1 receptor (CSF-1R)-related leukoencephalopathy (CRL) is a neurodegenerative disease that triggers early demyelination, leading to an adult-onset dementia. Triggering receptor expressed on myeloid cells-2 (TREM2) is a microglial receptor that promotes the activation of micr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biundo, Fabrizio, Chitu, Violeta, Gökhan, Şölen, Chen, Edward, Oppong-Asare, Jude, Stanley, E. Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452898/ https://www.ncbi.nlm.nih.gov/pubmed/37626591 http://dx.doi.org/10.3390/biomedicines11082094

Ejemplares similares

Differential regulation of microglial states by colony stimulating factors
por: Stanley, E. Richard, et al.
Publicado: (2023)

BSCI-18. ABLATION OF Csf2 MITIGATES RADIATION-INDUCED NEUROCOGNITIVE DECLINE INDEPENDENT OF HIPPOCAMPAL NEUROGENESIS
por: Gokhan, Sölen, et al.
Publicado: (2019)

Neuropsychological profile of CSF1R-related leukoencephalopathy
por: Rush, Beth K., et al.
Publicado: (2023)

Clinicopathologic characterization and abnormal autophagy of CSF1R-related leukoencephalopathy
por: Tian, Wo-Tu, et al.
Publicado: (2019)

Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy
por: Kempthorne, Liam, et al.
Publicado: (2020)

Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challenges
por: Han, Jinming, et al.
Publicado: (2022)

CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function
por: Pridans, Clare, et al.
Publicado: (2013)

Correction to: Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy
por: Kempthorne, Liam, et al.
Publicado: (2020)

Factors predictive of the presence of a CSF1R mutation in patients with leukoencephalopathy
por: Kondo, Y., et al.
Publicado: (2019)

Three novel mutations in Chinese patients with CSF1R-related leukoencephalopathy
por: Chu, Min, et al.
Publicado: (2021)

A Unique Radiological Correlate of CSF1R Mutation: “Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia - Sine Leukoencephalopathy“
por: Das, Shambaditya, et al.
Publicado: (2022)

Clinical and genetic characterization of adult‐onset leukoencephalopathy caused by CSF1R mutations
por: Tsai, Pei‐Chien, et al.
Publicado: (2021)

Adult‐onset leukoencephalopathy caused by CSF1R mutations: Is all that glitters gold?
por: Salsano, Ettore, et al.
Publicado: (2022)

CSF1R Related Leukoencephalopathy - Rare Childhood Presentation of An Autosomal Dominant Microgliopathy!
por: Sriram, Neeharika, et al.
Publicado: (2022)

Four Swedish cases of CSF1R‐related leukoencephalopathy: Visualization of clinical phenotypes
por: Rosenstein, Igal, et al.
Publicado: (2022)

Prophylactic Allogeneic Hematopoietic Stem Cell Therapy for CSF1R ‐Related Leukoencephalopathy
por: Horn, Morten Andreas, et al.
Publicado: (2022)

Increased CSF Soluble TREM2 Concentration in Patients With Neurosyphilis
por: Li, Wurong, et al.
Publicado: (2020)

Reply to: Adult‐onset leukoencephalopathy caused by CSF1R mutations: Is all that glitters gold?
por: Lee, Yi‐Chung, et al.
Publicado: (2022)

A Novel Missense Mutation of the CSF1R Gene Causes Incurable CSF1R-Related Leukoencephalopathy: Case Report and Review of Literature
por: Chen, Jie, et al.
Publicado: (2020)

Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945
por: Beckmann, Nicolau, et al.
Publicado: (2018)

COVID-19 leukoencephalopathy with subacute magnetic resonance imaging findings of vasculitis and demyelination
por: Vahedi, Ali, et al.
Publicado: (2021)

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling
por: Stables, Jennifer, et al.
Publicado: (2022)

Involvement of the optic nerve in mutated CSF1R-induced hereditary diffuse leukoencephalopathy with axonal spheroids
por: Shu, Yaqing, et al.
Publicado: (2016)

Functional characterization of a novel CSF1R mutation causing hereditary diffuse leukoencephalopathy with spheroids
por: Kraya, Torsten, et al.
Publicado: (2019)

Microglial replacement therapy: a potential therapeutic strategy for incurable CSF1R-related leukoencephalopathy
por: Han, Jinming, et al.
Publicado: (2020)

Dynamic analysis of CSF1R-related leukoencephalopathy on magnetic resonance imaging: a case report
por: Huang, Huasheng, et al.
Publicado: (2021)

Hematopoietic Stem Cell Transplantation in CSF1R-Related Leukoencephalopathy: Retrospective Study on Predictors of Outcomes
por: Dulski, Jarosław, et al.
Publicado: (2022)

Neuroinflammatory CSF biomarkers MIF, sTREM1, and sTREM2 show dynamic expression profiles in Alzheimer’s disease
por: Hok-A-Hin, Yanaika S., et al.
Publicado: (2023)

Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
por: Cheng, Baoying, et al.
Publicado: (2021)

Mutations in the colony stimulating factor 1 receptor (CSF1R) cause hereditary diffuse leukoencephalopathy with spheroids
por: Rademakers, Rosa, et al.
Publicado: (2011)

Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)
por: Li, Xin, et al.
Publicado: (2023)

Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Caused by a Novel R782G Mutation in CSF1R
por: Foulds, Nicola, et al.
Publicado: (2015)

Clinical and genetic characterization of adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia associated with CSF1R mutation
por: Konno, T., et al.
Publicado: (2016)

A novel CSF-1R mutation in a family with hereditary diffuse leukoencephalopathy with axonal spheroids misdiagnosed as hydrocephalus
por: Wang, Miaomiao, et al.
Publicado: (2019)

A Novel Splicing Mutation in the CSF1R Gene in a Family With Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids
por: Yang, Xiaodong, et al.
Publicado: (2019)

Clinical features and magnetic resonance image analysis of 15 cases of demyelinating leukoencephalopathy induced by levamisole
por: YAN, RUIFANG, et al.
Publicado: (2013)

CSF sTREM2: marking the tipping point between preclinical AD and dementia?
por: Schindler, Suzanne E, et al.
Publicado: (2016)

Dynamic changes of CSF sTREM2 in preclinical Alzheimer’s disease: the CABLE study
por: Ma, Ling-Zhi, et al.
Publicado: (2020)

African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants
por: Schindler, Suzanne E., et al.
Publicado: (2021)

CSF sTREM2 in delirium—relation to Alzheimer’s disease CSF biomarkers Aβ42, t-tau and p-tau
por: Henjum, Kristi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e5oe8a7qvdrlgfpvpe736kjhbi